Characterization of the atromentin biosynthesis genes and enzymes in the homobasidiomycete Tapinella panuoides.


This report highlights the first biochemical characterization of a multi-domain biosynthetic enzyme for basidiomycete secondary metabolism: the tri-domain enzyme atromentin synthetase AtrA, from Tapinella panuoides, which adenylates and dimerizes 4-hydroxyphenylpyruvic acid into atromentin. Also, the l-tyrosine:2-oxoglutarate aminotransferase AtrD, which… (More)
DOI: 10.1016/j.fgb.2008.08.009