Characterization of the Trichomonas vaginalis surface-associated AP65 and binding domain interacting with trichomonads and host cells

@article{Garcia2007CharacterizationOT,
  title={Characterization of the Trichomonas vaginalis surface-associated AP65 and binding domain interacting with trichomonads and host cells},
  author={Ana Cristina Ferreira Garcia and J. F. Alderete},
  journal={BMC Microbiology},
  year={2007},
  volume={7},
  pages={116 - 116}
}
AP65 is a prominent adhesin of Trichomonas vaginalis that mediates binding of parasites to host vaginal epithelial cells (VECs). AP65 with no secretion signal sequence, membrane targeting peptide, and anchoring motif was recently found to be secreted. We first wanted to demonstrate surface association of AP65 to the parasite followed by the identification of the binding epitope interacting with both organisms and VECs. AP65 was found to bind to trichomonads, but not to trypsin-treated parasites… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 21 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 38 references

Plasma antibodies against Trichomonas vaginalis and subsequent risk of prostate cancer.

Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology • 2006
View 1 Excerpt

Similar Papers

Loading similar papers…