Characterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis

@article{Graves2017CharacterizationOT,
  title={Characterization of the Tissue Distribution of the Mouse Cyp2c Subfamily by Quantitative PCR Analysis},
  author={Joan P. Graves and Artiom Gruzdev and J. Alyce Bradbury and Laura Miller Degraff and Matthew L. Edin and Darryl C. Zeldin},
  journal={Drug Metabolism and Disposition},
  year={2017},
  volume={45},
  pages={807 - 816}
}
The CYP2C subfamily of the cytochrome P450 gene superfamily encodes heme-thiolate proteins that have a myriad of biologic functions. CYP2C proteins detoxify xenobiotics and metabolize endogenous lipids such as arachidonic acid to bioactive eicosanoids. We report new methods and results for the quantitative polymerase reaction (qPCR) analysis for the 15 members of the mouse Cyp2c subfamily (Cyp2c29, Cyp2c37, Cyp2c38, Cyp2c39, Cyp2c40, Cyp2c44, Cyp2c50, Cyp2c54, Cyp2c55, Cyp2c65, Cyp2c66, Cyp2c67… 

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