Characterization of the T cell-mediated cellular cytotoxicity during acute infectious mononucleosis.

Abstract

Primary infection with EBV during acute infectious mononucleosis (IM) is associated with a cytotoxic response against allogeneic target cells. C depletion with anti-CD3 (OKT3) and anti-CD8 (OKT8) mAb decreased the allogeneic cytolysis of two EBV-infected lymphoblastoid cell lines (LCL) by 96% and 89%, respectively. Complement depletion with the NK cell… (More)

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@article{Tomkinson1989CharacterizationOT, title={Characterization of the T cell-mediated cellular cytotoxicity during acute infectious mononucleosis.}, author={Birgitta Tomkinson and Richard T Maziarz and J. L. Sullivan}, journal={Journal of immunology}, year={1989}, volume={143 2}, pages={660-70} }