Characterization of the Pharmacokinetics of Phosphatidylethanol 16:0/18:1 and 16:0/18:2 in Human Whole Blood After Alcohol Consumption in a Clinical Laboratory Study.

@article{Javors2016CharacterizationOT,
  title={Characterization of the Pharmacokinetics of Phosphatidylethanol 16:0/18:1 and 16:0/18:2 in Human Whole Blood After Alcohol Consumption in a Clinical Laboratory Study.},
  author={Martin A. Javors and Nathalie Hill-Kapturczak and John D. Roache and Tara E Karns-Wright and Donald M. Dougherty},
  journal={Alcoholism, clinical and experimental research},
  year={2016},
  volume={40 6},
  pages={
          1228-34
        }
}
BACKGROUND The purpose of this study was to characterize the pharmacokinetics of 2 homologues of phosphatidylethanol (PEth) and their combined total in uncoagulated, whole blood samples taken from participants in a human clinical laboratory study after consumption of low doses of ethanol (EtOH). METHODS As part of a larger study, 14 male and 13 female participants received either 0.25 or 0.50 g/kg oral doses of EtOH during a 15-minute period. Blood samples were collected before and throughout… CONTINUE READING
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