Characterization of the Novel Human Serotonin Receptor Subunits 5-HT3C,5-HT3D, and 5-HT3E

  title={Characterization of the Novel Human Serotonin Receptor Subunits 5-HT3C,5-HT3D, and 5-HT3E},
  author={Beate Niesler and Jutta Walstab and Sandra Combrink and Doroth{\'e}e M{\"o}ller and Johannes Kapeller and Jens Rietdorf and Heinz Bönisch and Manfred Göthert and Gudrun A. Rappold and Michael Brüss},
  journal={Molecular Pharmacology},
  pages={17 - 8}
Within the family of serotonin receptors, the 5-hydroxytryptamine-3 (5-HT3) receptor is the only ligand-gated ion channel. It is composed of five subunits, of which the 5-HT3A and 5-HT3B subunits are best characterized. Several studies, however, have reported on the functional diversity of native 5-HT3 receptors, which cannot solely be explained on the basis of the 5-HT3A and 5-HT3B subunits. After our discovery of further putative 5-HT3 serotonin receptor-encoding genes, HTR3C, HTR3D, and… 

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