Characterization of the EP-receptor mediating dilatation and potentiation of inflammation in rabbit skin.

@article{Armstrong1995CharacterizationOT,
  title={Characterization of the EP-receptor mediating dilatation and potentiation of inflammation in rabbit skin.},
  author={R. Armstrong and C. Marr and R. Jones},
  journal={Prostaglandins},
  year={1995},
  volume={49 4},
  pages={
          205-24
        }
}
The interactions of bradykinin (BK) and FMLP (a leukocyte-dependent mediator of inflammation) with thirteen prostaglandin E analogs have been investigated in a rabbit skin model of inflammation. The PGE analogs were chosen with a view to defining the EP-receptor subtypes involved. Five analogs, PGE2, misoprostol, 16,16-dimethyl PGE2, nocloprost, and enisoprost, were potent vasodilators (133Xe clearance method) and potent potentiators of both BK and FMLP exudation ([125I]albumin method). A… Expand
The anabolic effect of PGE2in rat bone marrow cultures is mediated via the EP4 receptor subtype.
Involvement of prostaglandins and histamine in nickel wire-induced acute inflammation in mice.
Dilatation and constriction of rat gastric mucosal microvessels through prostaglandin EP2 and EP3 receptors
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