Characterization of the CD40L/Oncostatin M/Oncostatin M receptor axis as an antiviral and immunostimulatory system disrupted in chronic HCV infection.

Abstract

BACKGROUND & AIMS Oncostatin M (OSM) is an inflammatory cytokine which interacts with a heterodimeric receptor formed by gp130 and either OSMRβ or LIFR. Here we have analysed OSM and its receptors in livers with chronic hepatitis C (CHC) and studied the factors that regulate this system. METHODS OSM, OSM receptors and OSM-target molecules were studied by… (More)
DOI: 10.1016/j.jhep.2013.10.016

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Cite this paper

@article{Larrea2014CharacterizationOT, title={Characterization of the CD40L/Oncostatin M/Oncostatin M receptor axis as an antiviral and immunostimulatory system disrupted in chronic HCV infection.}, author={Esther Larrea and Itziar Echeverria and J Ignacio Riezu-Boj and Rafael Aldabe and Laura Guembe and Iosu Sola and Mar{\'i}a Pilar Civeira and Pablo Sarobe and Jes{\'u}s Prieto}, journal={Journal of hepatology}, year={2014}, volume={60 3}, pages={482-9} }