Characterization of the BACH1 Helicase in the DNA Damage Response Pathway: a Dissertation

@inproceedings{Litman2007CharacterizationOT,
  title={Characterization of the BACH1 Helicase in the DNA Damage Response Pathway: a Dissertation},
  author={Rachel Litman},
  year={2007}
}
DNA damage response pathways are a complicated network of proteins that function to remove and/or reverse DNA damage. Following genetic insult, a signal cascade is generated, which alerts the cell to the presence of damaged DNA. Once recognized, the damage is either removed or the damaged region is excised, and the original genetic sequence is restored. However, when these pathways are defective the cell is unable to effectively mediate the DNA damage response and the damage persists unrepaired… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 166 REFERENCES

Mechanisms in eukaryotic mismatch repair.

  • The Journal of biological chemistry
  • 2006