Characterization of the Aryl Hydrocarbon Receptor and Aryl Hydrocarbon Responsiveness in Human Ovarian Carcinoma Cell Lines 1

  • C. Rowlands, V. Krishnan, +4 authors S. Langdon
  • Published 2006
The human ovarian carcinoma cell lines PE01, PE04, and PE06 express the estrogen receptor and studies with the PE04 cells have shown that tamoxifen inhibits 17ß-estradiol-induced proliferation. 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) is a broad spectrum antiestrogen which works through the aryl hydrocarbon receptor. Incubation of the three cell lines… (More)