Characterization of the 17p amplicon in human sarcomas: microsatellite marker analysis.

@article{Wolf1999CharacterizationOT,
  title={Characterization of the 17p amplicon in human sarcomas: microsatellite marker analysis.},
  author={Maija Wolf and Maija Tarkkanen and T. Hulsebos and Marcelo Luis Larramendy and Anne Forus and Ola Myklebost and Lauri A. Aaltonen and Inkeri Elomaa and Sakari Knuutila},
  journal={International journal of cancer},
  year={1999},
  volume={82 3},
  pages={329-33}
}
The structure of the 17p amplicon from 9 human sarcoma specimens evaluated by comparative genomic hybridization (CGH) has been studied by analyzing 28 microsatellite markers by PCR. Eleven sarcoma specimens showing no DNA copy number increases at 17p by CGH were analyzed as control samples. Five specimens were analyzed by Southern blotting using probes that have previously shown amplification at the 17p12 region in astrocytoma and high-grade osteosarcoma samples. Microsatellite marker analyses… CONTINUE READING

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