Characterization of temperate phages infecting Clostridium difficile isolates of human and animal origins.

@article{Sekulovic2014CharacterizationOT,
  title={Characterization of temperate phages infecting Clostridium difficile isolates of human and animal origins.},
  author={Ognjen Sekulovic and Julian R Garneau and Audrey N{\'e}ron and L C Fortier},
  journal={Applied and environmental microbiology},
  year={2014},
  volume={80 8},
  pages={2555-63}
}
Clostridium difficile is a Gram-positive pathogen infecting humans and animals. Recent studies suggest that animals could represent potential reservoirs of C. difficile that could then transfer to humans. Temperate phages contribute to the evolution of most bacteria, for example, by promoting the transduction of virulence, fitness, and antibiotic resistance genes. In C. difficile, little is known about their role, mainly because suitable propagating hosts and conditions are lacking. Here we… CONTINUE READING

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