Characterization of spermatogonial stem cell maturation and differentiation in neonatal mice.

@article{Mclean2003CharacterizationOS,
  title={Characterization of spermatogonial stem cell maturation and differentiation in neonatal mice.},
  author={D J Mclean and Patrick J Friel and D. St Johnston and Michael D Griswold},
  journal={Biology of reproduction},
  year={2003},
  volume={69 6},
  pages={2085-91}
}
Initiation of the first wave of spermatogenesis in the neonatal mouse testis is characterized by the differentiation of a transient population of germ cells called gonocytes found in the center of the seminiferous tubule. The fate of gonocytes depends upon these cells resuming mitosis and developing the capacity to migrate from the center of the seminiferous tubule to the basement membrane. This process begins approximately Day 3 postpartum in the mouse, and by Day 6 postpartum differentiated… CONTINUE READING