Characterization of shock-induced action potential extension during acute regional ischemia in rabbit hearts.

@article{Knisley1995CharacterizationOS,
  title={Characterization of shock-induced action potential extension during acute regional ischemia in rabbit hearts.},
  author={S. B. Knisley and Loraine K Holley},
  journal={Journal of cardiovascular electrophysiology},
  year={1995},
  volume={6 10 Pt 1},
  pages={775-85}
}
INTRODUCTION Defibrillation shocks produce extension of the myocardial action potential repolarization time (AP extension) in nonischemic myocardium. AP extension may synchronize repolarization in the heart because the extension increases when shock timing is increased. We tested whether AP extension occurs and whether it increases when shock timing is increased in regionally ischemic isolated perfused rabbit hearts stained with the transmembrane voltage sensitive fluorescent dye, di-4-ANEPPS… CONTINUE READING