Characterization of serum SHBG isoforms in prepubertal and pubertal girls.

  title={Characterization of serum SHBG isoforms in prepubertal and pubertal girls.},
  author={Patricia Bedecarr{\'a}s and Mirta Graciela Gryngarten and Sandra Ayuso and Mar{\'i}a Eugenia Escobar and C{\'e}sar Bergad{\'a} and Stella M. Campo},
  journal={Clinical endocrinology},
  volume={49 5},
OBJECTIVE SHBG is a circulating glycoprotein that binds dihydrotestosterone, testosterone and oestradiol with high affinity and low capacity. In girls, serum concentrations of SHBG gradually decrease with age due to a true fall in concentration and not to a change in the binding characteristics. The aim of our study was to determine the pattern of serum SHBG isoforms in normal girls in early childhood (ECh), late childhood (LCh) and puberty (P). SUBJECTS Fifteen normal girls were studied… CONTINUE READING


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