Characterization of rifampicin-resistant Mycobacterium tuberculosis in Taiwan.

  title={Characterization of rifampicin-resistant Mycobacterium tuberculosis in Taiwan.},
  author={Hsing-Yu Hwang and Christopher Chang and L Chang and Shui-Feng Chang and Ya-Hui Chang and Yi-jing Chen},
  journal={Journal of medical microbiology},
  volume={52 Pt 3},
Sixty-three rifampicin-resistant (Rif(r)) isolates of Mycobacterium tuberculosis from Kaohsiung, Taiwan, were analysed for mutations in the core region (69 bp, codons 511-533) of the rpoB gene. Some 84.1 % (53/63) of the resistant isolates showed mutations in this region, especially in codons 531 (41.5 %), 526 (18.9 %), 516 (15.1 %) and 533 (7.5 %). Five novel alleles of a total of 16 different types of mutations were identified in Rif(r) isolates. Ten Rif(r) isolates (15.9 %) exhibited no… CONTINUE READING
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Publications referenced by this paper.
Showing 1-10 of 37 references

Drug-resistant tuberculosis in Taipei, 1996-1999.

American journal of infection control • 2001
View 1 Excerpt