Characterization of retinal architecture in Parkinson's disease.

  title={Characterization of retinal architecture in Parkinson's disease.},
  author={Jessica Chorostecki and Navid Seraji-Bozorgzad and Aashka Shah and Fen Bao and Ginny Bao and Edwin B. George and Veronica Gorden and Christina Caon and Elliot M. Frohman and Muhammed T Bhatti and Omar A. Khan},
  journal={Journal of the neurological sciences},
  volume={355 1-2},
BACKGROUND Parkinson's disease (PD) is a neurodegenerative disorder associated with dopaminergic cell loss and α-synuclein aggregation in Lewy bodies, which has been demonstrated in the retina. METHODS We performed a spectral-domain optical coherence tomography (OCT) study in patients with PD and healthy controls to measure the peripapillary retinal nerve fiber layer thickness and macular volume. Intra-retinal segmentation was performed to measure the volume of the retinal nerve fiber (RNFL… CONTINUE READING
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