Characterization of reference materials for human antiserum to pertussis antigens by an international collaborative study.

@article{Xing2009CharacterizationOR,
  title={Characterization of reference materials for human antiserum to pertussis antigens by an international collaborative study.},
  author={Dorothy K-L Xing and Carl Heinz Wirsing von Koenig and Penny Newland and Marion Riffelmann and Bruce D. Meade and Michael Corbel and Rose E Gaines-Das},
  journal={Clinical and vaccine immunology : CVI},
  year={2009},
  volume={16 3},
  pages={303-11}
}
Enzyme-linked immunosorbent assay (ELISA) has been widely used to evaluate antibody responses to pertussis vaccination and infection. A common reference serum is essential for the standardization of these assays. However, no internationally recognized reference serum is available. At the request of the Expert Committee on Biological Standardization (ECBS) of the World Health Organization (WHO), a set of four candidate international standards has been prepared. These candidate materials have… CONTINUE READING

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