Characterization of reduced expression of glycine N-methyltransferase in cancerous hepatic tissues using two newly developed monoclonal antibodies.

Abstract

Glycine N-methyltransferase (GNMT) is a protein with multiple functions. Recently, two Italian siblings who had hepatomegaly and chronic elevation of serum transaminases were diagnosed to have GNMT deficiency caused by inherited compound heterozygosity of the GNMT gene with missence mutations. To evaluate the expression of GNMT in cell lines and tissues… (More)

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@article{Liu2003CharacterizationOR, title={Characterization of reduced expression of glycine N-methyltransferase in cancerous hepatic tissues using two newly developed monoclonal antibodies.}, author={Hsiao-Han Liu and Kuan-Hsuan Chen and Yi-Ping Shih and Wing-yiu Lui and F P Wong and Yi-Ming Arthur Chen}, journal={Journal of biomedical science}, year={2003}, volume={10 1}, pages={87-97} }