Characterization of proliferating cells in transient abnormal myelopoiesis: ultrastructural and immunocytochemical study.


A self-limited blastic proliferation, indistinguishable from acute leukemia except for its disappearance without therapy, has been noted in infants with Down's syndrome. This phenomenon is designated as transient abnormal myelopoiesis (TAM).1 The pro liferating blasts in TAM usually have been described as myeloblasts.2 Identification of megakaryoblasts is… (More)

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