Characterization of pre-antibiotic era Klebsiella pneumoniae isolates with respect to antibiotic/disinfectant susceptibility and virulence in Galleria mellonella.

@article{Wand2015CharacterizationOP,
  title={Characterization of pre-antibiotic era Klebsiella pneumoniae isolates with respect to antibiotic/disinfectant susceptibility and virulence in Galleria mellonella.},
  author={Matthew E Wand and Kate S Baker and Gabriel Benthall and Hannah McGregor and James W I McCowen and Ana Deheer-Graham and J. Mark Sutton},
  journal={Antimicrobial agents and chemotherapy},
  year={2015},
  volume={59 7},
  pages={3966-72}
}
The EGD Murray collection consists of approximately 500 clinical bacterial isolates, mainly Enterobacteriaceae, isolated from around the world between 1917 and 1949. A number of these "Murray" isolates have subsequently been identified as Klebsiella pneumoniae. Antimicrobial susceptibility testing of these isolates showed that over 30% were resistant to penicillins due to the presence of diverse blaSHV β-lactamase genes. Analysis of susceptibility to skin antiseptics and triclosan showed that… CONTINUE READING
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