Characterization of poliovirus conformational alteration mediated by soluble cell receptors.

@article{Yafal1993CharacterizationOP,
  title={Characterization of poliovirus conformational alteration mediated by soluble cell receptors.},
  author={Alicia G{\'o}mez Yafal and Gerardo Kaplan and Vincent R. Racaniello and James M. Hogle},
  journal={Virology},
  year={1993},
  volume={197 1},
  pages={501-5}
}
Soluble extracts of Spodoptera frugiperda cells expressing the poliovirus receptor (PVR) induce the native poliovirus (PV) to "A" particle conformational change (J. Virol. 64, 4697-4702). We describe the variables that regulate this passage and study the suitability of solubilized PVR both for use as an in vitro system to characterize the receptor-mediated conformational alteration and for the production of large amounts of altered virus for structural analysis. PVR seems to function in a… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 28 extracted citations

Molecular aspects of poliovirus pathogenesis

Proceedings of the Japan Academy. Series B, Physical and biological sciences • 2007

Similar Papers

Loading similar papers…