Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis.

@article{Portnoy1981CharacterizationOP,
  title={Characterization of plasmids and plasmid-associated determinants of Yersinia enterocolitica pathogenesis.},
  author={Daniel A Portnoy and Steve L. Moseley and Stanley Falkow},
  journal={Infection and immunity},
  year={1981},
  volume={31 2},
  pages={
          775-82
        }
}
Yersinia enterocolitica isolates harboring a particular species of plasmid deoxyribonucleic acid showed a high degree of lethality for gerbils and caused the detachment of HEp-2 tissue cell monolayers. Strains cured of their plasmid deoxyribonucleic acid showed loss of these properties. However, invasiveness of HEp-2 cells was shown not to be a plasmid-mediated property. The expression of plasmid-associated properties, including at least three major outer membrane polypeptides, occurred during… CONTINUE READING

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