Characterization of peripherin/rds and rom-1 transport in rod photoreceptors of transgenic and knockout animals.

@article{Lee2006CharacterizationOP,
  title={Characterization of peripherin/rds and rom-1 transport in rod photoreceptors of transgenic and knockout animals.},
  author={Edwin S. Lee and Beth Burnside and John G Flannery},
  journal={Investigative ophthalmology & visual science},
  year={2006},
  volume={47 5},
  pages={2150-60}
}
PURPOSE Peripherin/rds and rom-1 have structural roles in morphogenesis and stabilization of the outer segment, but little is known about their transport and sorting to the rod outer segment. Peripherin/rds and rom-1 trafficking were studied in several knockout and transgenic animal models. METHODS Rod outer segment formation and distribution of peripherin/rds and rom-1 were examined by immunohistochemistry, electron microscopy, and molecular biological methods in wild-type, rhodopsin… CONTINUE READING