Characterization of patients with angioedema without wheals: the importance of F12 gene screening.

@article{Firinu2015CharacterizationOP,
  title={Characterization of patients with angioedema without wheals: the importance of F12 gene screening.},
  author={Davide Firinu and Valeria Bafunno and Gennaro Vecchione and Maria Pina Barca and Paolo Emilio Manconi and Rosa Santacroce and Maurizio Margaglione and Stefano R Del Giacco},
  journal={Clinical immunology},
  year={2015},
  volume={157 2},
  pages={239-48}
}
Sporadic and familiar forms of non-histaminergic angioedema and normal C1 inhibitor encompass a group of disorders possibly caused by bradikinin. We aimed to study the subgroups of hereditary angioedema with FXII mutation (FXII-HAE), unknown genetic defect (U-HAE) and idiopathic non-histaminergic acquired angioedema (InH-AAE). We screened the F12 locus in… CONTINUE READING