Characterization of partial gene deletions in type III von Willebrand disease with alloantibody inhibitors.

Abstract

von Willebrand factor gene deletions were characterized in four patients with severe type III von Wilebrand disease and alloantibodies to von Willebrand factor. A PCR-based strategy was used to characterize the boundaries of the deletions. Identical 30 kb von Willebrand factor gene deletions which include exons 33 through 38 were identified in two siblings… (More)

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@article{Mancuso1994CharacterizationOP, title={Characterization of partial gene deletions in type III von Willebrand disease with alloantibody inhibitors.}, author={David J Mancuso and Elodee A. Tuley and Roel Beltran Castillo and N Blumenfeld De Bosch and Pablo Mannucci and Jonathan Sadler}, journal={Thrombosis and haemostasis}, year={1994}, volume={72 2}, pages={180-5} }