Characterization of pandemic influenza immune memory signature after vaccination or infection.

@article{Bonduelle2014CharacterizationOP,
  title={Characterization of pandemic influenza immune memory signature after vaccination or infection.},
  author={Olivia Bonduelle and Fabrice Carrat and Charles-Edouard Luyt and Catherine Leport and Anne Mosnier and Nora Benhabiles and Anne Krivine and Flore Rozenberg and Nora Yahia and Assia Samri and Dominique Rousset and Sylvie van der Werf and Brigitte Autran and B{\'e}hazine Combadi{\`e}re},
  journal={The Journal of clinical investigation},
  year={2014},
  volume={124 7},
  pages={
          3129-36
        }
}
The magnitude, quality, and maintenance of immunological memory after infection or vaccination must be considered for future design of effective influenza vaccines. In 2009, the influenza pandemic produced disease that ranged from mild to severe, even fatal, illness in infected healthy adults and led to vaccination of a portion of the population with the adjuvanted, inactivated influenza A(H1N1)pdm09 vaccine. Here, we have proposed a multiparameter quantitative and qualitative approach to… CONTINUE READING

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