Characterization of pancreatic ductal cells in human islet preparations

  title={Characterization of pancreatic ductal cells in human islet preparations},
  author={Hirohito Ichii and Atsushi Miki and Toshiyuki Yamamoto and Ruth Damaris Molano and Scott J. Barker and Atsuyoshi Mita and Rayner Rodriguez-Diaz and D. Klein and Ricardo Luis Pastori and Rodolfo Alejandro and Luca Alessandro Inverardi and Antonello Pileggi and Camillo Ricordi},
  journal={Laboratory Investigation},
Substantial amounts of nonendocrine cells are implanted as part of human islet grafts, and a possible influence of nonendocrine cells on clinical islet transplantation outcome has been postulated. There are currently no product release criteria specific for nonendocrine cells due to lack of available methods. The aims of this study were to develop a method for the evaluation of pancreatic ductal cells (PDCs) for clinical islet transplantation and to characterize them regarding phenotype… CONTINUE READING
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