Characterization of overt carnitine palmitoyltransferase in rat platelets; involvement of insulin on its regulation

@article{Iida1991CharacterizationOO,
  title={Characterization of overt carnitine palmitoyltransferase in rat platelets; involvement of insulin on its regulation},
  author={Reimi Iida and Naoshi Takeyama and Naohiro Iida and Takaya Tanaka},
  journal={Molecular and Cellular Biochemistry},
  year={1991},
  volume={103},
  pages={23-30}
}
Saponin-permeabilization (30 µg/ml) of the platelet plasma membrane, which enables access of added compounds to mitochondrial overt carnitine palmitoyltransferase (CPT I), was applied to allow the rapid determination of CPT I activity in situ. The effects of diabetes and short-term incubation with insulin in vitro on the kinetic parameters and malonyl-CoA… CONTINUE READING