Characterization of oestrogen receptors in zebrafish (Danio rerio).

@article{Bardet2002CharacterizationOO,
  title={Characterization of oestrogen receptors in zebrafish (Danio rerio).},
  author={P-L Bardet and B{\'e}atrice Horard and Marc Robinson-Rechavi and Vincent Laudet and J-M Vanacker},
  journal={Journal of molecular endocrinology},
  year={2002},
  volume={28 3},
  pages={153-63}
}
We cloned the cDNAs corresponding to three oestrogen receptors (ERs) in zebrafish (Danio rerio). Sequence analysis and phylogenetic studies demonstrated that two of these genes, ER beta.1 and ER beta.2, arose from duplication of the original ER beta in many species of the fish phylum, whereas ER alpha is unique. Zebrafish ERs behaved as oestrogen-dependent transcription factors in transactivation assays. However, their reactivity to various oestrogen modulators was different compared with that… CONTINUE READING
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  • EV Jensen, S Nilsson, M Warner, J-A Gustafsson
  • 2001

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