Characterization of octopamine-sensitive adenylate cyclase: elucidation of a class of potent and selective octopamine-2 receptor agonists with toxic effects in insects.

@article{Nathanson1985CharacterizationOO,
  title={Characterization of octopamine-sensitive adenylate cyclase: elucidation of a class of potent and selective octopamine-2 receptor agonists with toxic effects in insects.},
  author={J. A. Nathanson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1985},
  volume={82 2},
  pages={599-603}
}
  • J. A. Nathanson
  • Published 1985 in
    Proceedings of the National Academy of Sciences…
Octopamine-2 receptors, associated with activation of adenylate cyclase, mediate a number of the important hormonal and neurotransmitter functions of octopamine in invertebrates. By utilizing the highly enriched octopamine-sensitive adenylate cyclase present in the firefly light organ, it has been possible to pharmacologically characterize octopamine-2 receptors and to define a new class of highly potent and selective octopamine-2 agonists. At low concentrations, these substituted… CONTINUE READING

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