Characterization of novel ascidian β integrins as primitive complement receptor subunits

@article{Miyazawa2004CharacterizationON,
  title={Characterization of novel ascidian $\beta$ integrins as primitive complement receptor subunits},
  author={S. Miyazawa and M. Nonaka},
  journal={Immunogenetics},
  year={2004},
  volume={55},
  pages={836-844}
}
Integrin-type complement receptors play pivotal roles in the effector mechanisms of the complement system. Previously, we identified an integrin α subunit, αHr1, from the solitary ascidian, Halocynthia roretzi, which is involved in the complement-dependent phagocytic activities of ascidian hemocytes. To identify integrin β subunits that pair with αHr1 to compose ascidian complement receptors, genes encoding β subunits were cloned and characterized for their binding property to αHr1. Using… Expand
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