Characterization of nonconservative homologous junctions in mammalian cells.

@article{Desautels1990CharacterizationON,
  title={Characterization of nonconservative homologous junctions in mammalian cells.},
  author={Lyne Desautels and Suzanne Brouillette and J C Wallenburg and Abdellah Belmaaza and Nadine Gusew and P Trudel and Pascal Chartrand},
  journal={Molecular and cellular biology},
  year={1990},
  volume={10 12},
  pages={6613-8}
}
Homologous recombination in mammalian cells between extrachromosomal molecules, as well as between episomes and chromosomes, can be mediated by a nonconservative mechanism. It has been proposed that the key steps in this process are the generation (by double-strand cleavage) of overlapping homologous ends, the creation of complementary single-strand ends… CONTINUE READING