Characterization of neutralization epitopes on the VP7 surface protein of serotype G11 porcine rotaviruses.

@article{Ciarlet1994CharacterizationON,
  title={Characterization of neutralization epitopes on the VP7 surface protein of serotype G11 porcine rotaviruses.},
  author={Max Ciarlet and Mayra A Hidalgo and Marina Gorziglia and Ferdinando Liprandi},
  journal={The Journal of general virology},
  year={1994},
  volume={75 ( Pt 8)},
  pages={1867-73}
}
Rotavirus strain A253, isolated from the faeces of a diarrhoeic piglet in Venezuela, was classified as serotype G11 by cross-neutralization studies and by comparison of the deduced amino acid sequence of the VP7 surface protein. The epitopes involved in neutralization of the two G11 porcine rotavirus strains A253 and YM were analysed using neutralization-resistant mutants selected with seven neutralizing monoclonal antibodies (MAbs), monotype-specific (M-) MAbs and serotype-specific (S-) MAbs… CONTINUE READING