Characterization of nano oxaliplatin prepared by novel Fat Employing Supercritical Nano System, the FESNS®.

@article{Lee2012CharacterizationON,
  title={Characterization of nano oxaliplatin prepared by novel Fat Employing Supercritical Nano System, the FESNS®.},
  author={Seung-Jae Lee and Young-Hoon Kim and Sang-Heon Lee and Mikyoung Hahn},
  journal={Pharmaceutical development and technology},
  year={2012},
  volume={17 2},
  pages={212-8}
}
BACKGROUND Oxaliplatin has long been used for the treatment of colorectal cancer via intra-venous infusion. In order to improve patient compliance, a solid dosage form for oral administration of oxaliplatin was prepared as nano-sized particles. METHOD Nano oxaliplatin was prepared employing Fat Employing Supercritical Nano System (FESNS(®)) with Supercritical Fluid (SCF) apparatus by using myristyl alcohol as solvent. Morphology of nano oxaliplatin was examined by Scanning Electron Microscopy… CONTINUE READING