Characterization of mutant alleles of myospheroid, the gene encoding the beta subunit of the Drosophila PS integrins.

@article{Bunch1992CharacterizationOM,
  title={Characterization of mutant alleles of myospheroid, the gene encoding the beta subunit of the Drosophila PS integrins.},
  author={Thomas A. Bunch and R Salatino and M C Engelsgjerd and Leona Mukai and Richard F. West and Danny L. Brower},
  journal={Genetics},
  year={1992},
  volume={132 2},
  pages={519-28}
}
This paper presents the characterization of nine alleles of myospheroid, which encodes the beta PS subunit of the Drosophila PS integrins. On Southern blots, the mysXB87, mysXN101 and mysXR04 genes yield restriction digest patterns similar to that seen for wild-type chromosomes, however the mys1 and mysXG43 genes contain detectable deletions. mys1, mysXB87 and mysXG43 make little or no stable protein product, and genetically behave as strong lethal alleles. For the mysXN101 mutation, protein… CONTINUE READING

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