Characterization of muscarinic receptor subtypes on human peripheral lung.

@article{Casale1988CharacterizationOM,
  title={Characterization of muscarinic receptor subtypes on human peripheral lung.},
  author={Thomas B. Casale and P Ecklund},
  journal={Journal of applied physiology},
  year={1988},
  volume={65 2},
  pages={594-600}
}
To better define the role of muscarinic receptors in lung responses and airway diseases, we characterized the binding of the M1-specific antagonist, [3H]pirenzepine (PZ), and the nonspecific (M1- and M2-) antagonist, [3H]quinuclidinyl benzilate (QNB), to human peripheral lung tissue. Data obtained from 15 different lung specimens showed that the… CONTINUE READING