Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats.

@article{Abe2003CharacterizationOM,
  title={Characterization of muscarinic receptor subtypes in the rostral ventrolateral medulla and effects on morphine-induced antinociception in rats.},
  author={Kenji Abe and Kyoji Taguchi and Masatoshi Kato and Iku Utsunomiya and Toshiyuki Chikuma and Hiroshi Hojyo and Tadashi Miyatake},
  journal={European journal of pharmacology},
  year={2003},
  volume={465 3},
  pages={237-49}
}
The present study investigated the role of muscarinic receptor subtypes in the nucleus reticularis gigantocellularis/nucleus reticularis gigantocellularis alpha of the rat rostral ventrolateral medulla in morphine-induced antinociception. The antinociceptive effects of morphine were evoked by systemic administration or microinjection into the nucleus reticularis gigantocellularis/nucleus reticularis gigantocellularis alpha. Administration of morphine produced antinociception for hot plate and… CONTINUE READING