Characterization of mouse and human B7-H3 genes.

  title={Characterization of mouse and human B7-H3 genes.},
  author={Mingyi Sun and Sabrina Richards and Durbaka V.R. Prasad and Xoi Muoi Mai and Alexander Yu. Rudensky and Chen Dong},
  journal={Journal of immunology},
  volume={168 12},
T cell activation and immune function are regulated by costimulatory molecules of the B7 superfamily. Human B7-H3 is a recent addition to this family and has been shown to mediate T cell proliferation and IFN-gamma production. In this work we describe the identification of the mouse B7-H3 homolog, which is ubiquitously expressed in a variety of tissues… CONTINUE READING