Characterization of monocyte-derived dendritic cells from cats infected with feline immunodeficiency virus.

@article{Mizukoshi2009CharacterizationOM,
  title={Characterization of monocyte-derived dendritic cells from cats infected with feline immunodeficiency virus.},
  author={Fuminori Mizukoshi and Kenji Baba and Hiroshi Horiuchi and Yuko Goto-Koshino and Asuka Setoguchi-Mukai and Yasuhito Fujino and Koichi Ohno and Peter Francis Moore and Hajime Tsujimoto},
  journal={The Journal of veterinary medical science},
  year={2009},
  volume={71 7},
  pages={
          865-71
        }
}
Dendritic cells (DCs) are professional antigen presenting cells (APCs) that possess an extraordinary capacity to stimulate naïve T cells and initiate a primary immune response. To develop a DC-based immunotherapy for feline immunodeficiency virus (FIV) infection, we carried out a study to characterize DCs from FIV-infected cats and compared the observations with those obtained from healthy controls. DCs were derived from adherent peripheral blood mononuclear cells that had been cultivated with… CONTINUE READING