Characterization of monoclonal antibodies raised against the latent nuclear antigen of human herpesvirus 8.

@article{Kellam1999CharacterizationOM,
  title={Characterization of monoclonal antibodies raised against the latent nuclear antigen of human herpesvirus 8.},
  author={Paul Kellam and Dimitra Bourboulia and Nicolas Dupin and Christine F Shotton and Clare Fisher and Suzanne Talbot and Chris Boshoff and Robin A Weiss},
  journal={Journal of virology},
  year={1999},
  volume={73 6},
  pages={5149-55}
}
Human herpesvirus 8 (HHV-8; also designated Kaposi's sarcoma-associated herpesvirus) is the likely etiological agent of Kaposi's sarcoma (KS). HHV-8 encodes a latent nuclear antigen (LNA) which is the product of the viral gene orf 73. LNA is recognized by most infected patient sera and is the basis of current immunofluorescence assays used in epidemiological studies of HHV-8 infection. Here we describe the characterization of four monoclonal antibodies raised to the C-terminal third of LNA… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 22 extracted citations

NF-κB as a target for oncogenic viruses.

Current topics in microbiology and immunology • 2011
View 9 Excerpts
Highly Influenced

Hematological Malignancies

Methods in Molecular Biology • 2013

References

Publications referenced by this paper.
Showing 1-10 of 33 references

Similar Papers

Loading similar papers…