Characterization of monoclonal antibodies against a type SAT 2 foot-and-mouth disease virus.

@article{Crowther1993CharacterizationOM,
  title={Characterization of monoclonal antibodies against a type SAT 2 foot-and-mouth disease virus.},
  author={John Crowther and Cheryl A. Rowe and Rebecca Butcher},
  journal={Epidemiology and infection},
  year={1993},
  volume={111 2},
  pages={391-406}
}
This paper is the first to describe characterization of monoclonal antibodies (MAbs) against a South African Territories 2 (SAT 2) foot-and-mouth disease virus (isolate Rho 1/48). Twelve MAbs which neutralized homologous virus were characterized in indirect and sandwich ELISA using purified Rho 1/48 virus particles, subunits, trypsin-treated, and chemically denatured virus. All the MAbs inhibited haemagglutination by parental virus. Binding of the MAbs to 73 SAT 2 field isolates was measured in… CONTINUE READING
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