Characterization of microtubule-associated protein phosphoisoforms present in isolated growth cones.

The presence of microtubule-associated proteins (MAPs) in growth cones has been analyzed by isolation of these structures and characterization of their proteins by immunofluorescence studies. Two major MAPs, MAP1B and tau, were present in growth cones of cerebellum neurons isolated from 5-day-old rats. Both MAPs could be modified by proline-dependent… (More)