Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer.

@article{Gong2014CharacterizationOM,
  title={Characterization of microRNA-29 family expression and investigation of their mechanistic roles in gastric cancer.},
  author={Jianan Gong and Jianxiong Li and Yi Wang and Changzheng Liu and Hongyan Jia and Chongliang Jiang and Yuxuan Wang and Min Luo and Hongmei Zhao and Lei Dong and Wei Song and Fang Wang and Weibin Wang and Junwu Zhang and Jia Yu},
  journal={Carcinogenesis},
  year={2014},
  volume={35 2},
  pages={497-506}
}
Increasing evidence shows that abnormal microRNAs (miRNAs) expression is involved in tumorigenesis. They might be the novel biomarkers or therapeutic targets in disease treatment. miR-29 family was previously reported to act as tumor suppressors or oncogenes in diverse cancers. However, their accurate expression, function and mechanism in gastric cancer (GC) are not well known. Here, we found that the expression of miR-29 family members was significantly reduced in GC compared with adjacent… CONTINUE READING

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