Characterization of melanoma-associated surface antigens involved in the adhesion and motility of human melanoma cells.

@article{Vries1986CharacterizationOM,
  title={Characterization of melanoma-associated surface antigens involved in the adhesion and motility of human melanoma cells.},
  author={Jan de Vries and Gladys Keizer and Anje A. te Velde and Arie C. Voordouw and Dirk J. Ruiter and Ph. R{\"u}mke and Hergen Spits and C G Figdor},
  journal={International journal of cancer},
  year={1986},
  volume={38 4},
  pages={
          465-73
        }
}
The functional properties of the melanoma-associated antigens detected by monoclonal antibodies (MAbs) AMF-6 and AMF-7 were investigated. These MAbs were selected previously because of their capacity to block the anti-melanoma reactivity of cytotoxic T-lymphocyte clones AMF-6 and AMF-7 detect a melanoma-associated proteoglycan (MW greater than 450-250 kDa) and a molecular complex, which under reducing conditions consists of 4 compounds of 120, 95, 29 and 25 kDa respectively. AMF-6 reacted… CONTINUE READING
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