Characterization of measles virus recovered from persistently infected Vero cells.

  title={Characterization of measles virus recovered from persistently infected Vero cells.},
  author={I. Prasad and A. Mnere},
  journal={Japanese journal of medical science \& biology},
  volume={33 6},
  • I. Prasad, A. Mnere
  • Published 1980
  • Biology, Medicine
  • Japanese journal of medical science & biology
Vero cells were persistently infected with measles virus in medium with antimeasles serum. When antiserum was not added to the medium, the persistently infected cells (VMAS cells) proliferated in a cyclical manner alternating between extensive cell destruction and renewed cell growth. When these cells were grown at 33 C and 40 C, they released temperature-sensitive and temperature-dependent viruses. However, these viruses, upon further propagation, reverted to the wild type suggesting that such… Expand
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