Characterization of malT mutants that constitutively activate the maltose regulon of Escherichia coli.

@article{Dardonville1990CharacterizationOM,
  title={Characterization of malT mutants that constitutively activate the maltose regulon of Escherichia coli.},
  author={B Dardonville and Olivier Raibaud},
  journal={Journal of bacteriology},
  year={1990},
  volume={172 4},
  pages={1846-52}
}
The expression of the maltose regulon of Escherichia coli is controlled by a transcriptional activator, the product of the malT gene, and is induced by the presence of maltose or maltodextrins in the growth medium. We isolated eight mutants with mutations in malT which lead to constitutive expression of the regulon. The nucleotide sequences of the mutated genes revealed that the eight mutations are clustered in two small regions in the first one-third of the malT gene. Two mutated MalT proteins… CONTINUE READING