Characterization of lymphocytic infiltrates in normal, preneoplastic, and neoplastic mouse mammary tissues.

@article{Wei1986CharacterizationOL,
  title={Characterization of lymphocytic infiltrates in normal, preneoplastic, and neoplastic mouse mammary tissues.},
  author={Wei Wei and Kevin Malone and Kathleen Mahoney and Gloria H. Heppner},
  journal={Cancer research},
  year={1986},
  volume={46 6},
  pages={2680-5}
}
Lymphocytic infiltrates were isolated from normal, preneoplastic, and neoplastic mouse mammary tissues. The surface markers on the infiltrating lymphocytes were characterized by immunofluorescent staining and flow cytometry. Preneoplastic and neoplastic tissues contained 10- to 20-fold more in situ lymphocytes than did the normal pregnant gland. Most of these lympocytes were T-cells. Relative to the T-cells in normal gland, the T-cells in C4 preneoplastic hyperplastic alveolar nodules and their… CONTINUE READING

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