Characterization of lymphocytic choriomeningitis virus-binding protein(s): a candidate cellular receptor for the virus.

@article{Borrow1992CharacterizationOL,
  title={Characterization of lymphocytic choriomeningitis virus-binding protein(s): a candidate cellular receptor for the virus.},
  author={Persephone Borrow and Michael B A Oldstone},
  journal={Journal of virology},
  year={1992},
  volume={66 12},
  pages={7270-81}
}
The attachment of lymphocytic choriomeningitis virus (LCMV) to murine and primate cell lines was quantitated by a fluorescence-activated cell sorter assay in which binding of biotinylated virus was detected with streptavidin-fluorescein isothiocyanate. Cell lines that were readily infected by LCMV (e.g., MC57, Rin, BHK, Vero, and HeLa) bound virus in a dose-dependent manner, whereas no significant binding was observed to lymphocytic cell lines (e.g., RMA and WIL 2) that were not readily… CONTINUE READING
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