Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.

@article{Rao2008CharacterizationOL,
  title={Characterization of lens fiber cell triton insoluble fraction reveals ERM (ezrin, radixin, moesin) proteins as major cytoskeletal-associated proteins.},
  author={Ponugoti Vasantha Rao and Tammy Ho and Nikolai P Skiba and Rupalatha Maddala},
  journal={Biochemical and biophysical research communications},
  year={2008},
  volume={368 3},
  pages={508-14}
}
To understand lens fiber cell elongation- and differentiation-associated cytoskeletal remodeling, here we identified and characterized the major protein components of lens fiber cell Triton X-100 insoluble fraction by mass spectrometry and immunoblot analysis. This analysis identified spectrin, filensin, vimentin, tubulin, phakinin, and beta-actin as major… CONTINUE READING